Phyto-chemical study and in vitro glucophage activity of Laportea aestuans (l.) Chew. (Urticaceae)

Abstract

In this study, we carried out a phytochemical analysis and an evaluation of the glucophage activity of Laportea aestuans leaves. Several parameters were studied, such as physical characteristics, chemical screening and glucophage activity. The results showed that the dry leaves of Laportea aestuan have a moisture content of 1.6 %, an ash content of 14.9 % and a dry mater content of 98.4 %. The leaves contain major groups of secondary metabolites such as that polyphenols, flavonoids, bound quinines, anthocyanins, leuco-anthocyanins, alkaloids, saponins and steroids and there is an absence of triterpenes, free quinines. Leaves of Laportea aestuans have also glucophage activity.

Keywords: Phytochemical, Laportea aestuans, hyperglycemia, Kinshasa, RDCongo